Category: OTHER HEMATOLOGY | Code: K1002
ACA IgM
Function
Anticardiolipin antibodies (ACA) is a group of autoantibodies that attack cardiolipin (a substance contained in cells and platelets). This examination is useful for establishing the diagnosis of anti-phospholipid syndrome (APS). ACA autoantibody activity can cause several diseases, such as autoimmune disease, recurrent abortion, and blood clotting disease. ACA examination consists of ACA IgG and IgM tests.
| Test Schedule | Estimated Test Result | Container | Substance | Stability |
|---|---|---|---|---|
| Monday - Saturday < 10 am | 1 day | Plain | Serum, 1 mL | 4-8 hours 2 - 8⁰C, >2 days freezer |
Condition
Not lysate and not lipemic
Method
Enzyme-linked immunosorbent assay (ELISA) detecting isotype-specific ACA binding to a microtiter plate coated with purified cardiolipin antigen
Score Reference
• IgG: − Negative: <15 GPL − Indeterminate: 15−20 GPL − Low-medium positive: >20−80 GPL − Positive: >80 GPL • IgM: − Negative: <13 MPL − Indeterminate: 13−20 MPL − Low-medium positive: >20−80 MPL − Positive: >80 MPL